Neuromodulazione Sacrale (NMS)

Terapia di provata efficacia nell’incontinenza urinaria, e di efficacia promettente, secondo studi in fase di definizione, anche come trattamento dell’incontinenza fecale, del dolore perineale cronico, di disturbi espulsivi uro- e proctologici, anche in soggetti mielolesi e affetti da neuropatologie organiche (Vedi PNE).

  1. Bannowsky A, Wefer B, Braun PM, Jünemann KP. Urodynamic changes and response rates in patients treated with permanent electrodes compared to conventional wire electrodes in the peripheral nerve evaluation test. World J Urol 2008 Dec;26(6):623-6 ;
  2. De Sèze M, Delleci C, Denys P, Amarenco G. Peripheral electrical stimulation in neurogenic bladder. Ann Readapt Med Phys
    2008;51(6):473-8;
  3. Groenendijk PM, Lycklama à Nyeholt AA, Heesakkers JP, van Kerrebroeck PE, Hassouna MM, Gajewski JB, Cappellano F, Siegel SW, Fall M, Dijkema HE, Jonas U, van den Hombergh U. Sacral Nerve Stimulation Study Group. Urodynamic evaluation of sacral neuromodulation for urge urinary incontinence. BJU Int 2008;101(3):325-9;
  4. Chartier-Kastler E. Sacral neuromodulation for treating the symptoms of overactive bladder syndrome and non-obstructive urinary retention: >10 years of clinical experience. BJU Int 2008;101(4):417-23;
  5. Zabihi N, Mourtzinos A, Maher MG, Raz S, Rodríguez LV. The effects of bilateral caudal epidural S2-4 neuromodulation on female sexual function. Int Urogynecol J Pelvic Floor Dysfunct 2008;19(5):697-700;
  6. Vignes JR, de Seze M, Guerin J, Barat M. Sacral neuromodulation as a functional treatment of bladder overactivity. Acta Neurochir
    2007;97:315-22.
  7. Lumi CM, Muñoz JP, La Rosa L. Sacral neuromodulation in fecal incontinence. Apilot prospective experience in Argentina. Acta Gastroenterol Latinoam 2007;37(1):29-36.
  8. Hijaz A, Vasavada SP, Daneshgari F, Frinjari H, Goldman H, Rackley R. Complications and troubleshooting of two-stage sacral neuromodulation therapy: a single-institution experience. Urology 2006;68(3):533-7;
  9. Van Voskuilen AC, Oerlemans DJ, Weil EH, van den Hombergh U, van Kerrebroeck PE. Medium-term experience of sacral neuromodulation by tined lead implantation. BJU Int 2007;99(1):107-10;.
  10. Seif C, Bannowsky A, Wefer B, Naumann VC, van der Horst C, Jünemann KP, Braun PM. Use of permanent electrodes in the peripheral nerve evaluation test (PNE-Test) in comparison to conventional wire electrodes. Aktuelle Urol 2006;37(4):277-80;
  11. Pauls RN, Marinkovic SP, Silva WA, Rooney CM, Kleeman SD, Karram MM. Effects of sacral neuromodulation on female sexual function. Int Urogynecol J Pelvic Floor Dysfunct 2007;18(4):391-5;
  12. Daneshgari F. Applications of neuromodulation of the lower urinary tract in female urology. Int Braz J Urol 2006;32(3):262-72;
  13. Michelsen HB, Buntzen S, Krogh K, Laurberg S. Rectal volume tolerability and anal pressures in patients with fecal incontinence treated with sacral nerve stimulation. Dis Colon Rectum. 2006 Jul;49(7):1039-44;
  14. Uludag O, Morren GL, Dejong CH, Baeten CG. Effect of sacral neuromodulation on the rectum. Br J Surg 2005;92(8):1017-23;
  15. Spinelli M, Malaguti S, Giardiello G, Lazzeri M, Tarantola J, Van Den Hombergh U. A new minimally invasive procedure for pudendal nerve stimulation to treat neurogenic bladder: description of the method and preliminary data. Neurourol Urodyn 2005;24
    (4):305-9;
  16. Elhilali MM, Khaled SM, Kashiwabara T, Elzayat E, Corcos J. Sacral neuromodulation: long-term experience of one center. Urology
    2005;65(6):1114-7.
  17. Amoroso L, Pelliccioni G, Ghiselli R, Scarpino O, Saba V, Ricci S. Sacral-neuromodulation CT-guided. Radiol Med 2005 ;109(4):
    421-9;
  18. Kessler TM, Madersbacher H, Kiss G. Prolonged sacral neuromodulation testing using permanent leads: a more reliable patient selection method? Eur Urol. 2005 May;47(5):660-5. Epub 2005 Jan 4;
  19. Ratto C, Grillo E, Parello A, Petrolino M, Costamagna G, Doglietto GB. Sacral neuromodulation in treatment of fecal incontinence following anterior resection and chemoradiation for rectal cancer. Dis Colon Rectum. 2005 May;48(5):1027-36;
  20. Pillinger SH, Gardiner A, Duthie GS. Sacral nerve stimulation for faecal incontinence. Dig Surg 2005;22(1-2):1-5;
  21. Uluda O, Koch SM, van Gemert WG, Dejong CH, Baeten CG. Sacral neuromodulation in patients with fecal incontinence: a singlecenter
    study. Dis Colon Rectum 2004;47(8):1350-7;
  22. Guys JM, Haddad M, Planche D, Torre M, Louis-Borrione C, Breaud J. Sacral neuromodulation for neurogenic bladder dysfunction in children. J Urol 2004;172:1673-6;
  23. Roupret M, Chartier-Kastler E, Almeras C, Ayoub N, Haertig A, Richard F. Sacral neuromodulation for refractory detrusor overactivity in women with an artificial urinary sphincter. J Urol 2004;172(1):236-9;
  24. Everaert K, Kerckhaert W, Caluwaerts H, Audenaert M, Vereecke H, De Cuypere G, Boelaert A, Van den Hombergh U, Oosterlinck W. A prospective randomized trial comparing the 1-stage with the 2-stage implantation of a pulse generator in patients with pelvic floor dysfunction selected for sacral nerve stimulation. Eur Urol 2004;45(5):649-54;
  25. Malaguti S, Spinelli M, Giardiello G, Lazzeri M, Van Den Hombergh U. Neurophysiological evidence may predict the outcome of sacral neuromodulation. J Urol. 2003;170:2323-6;
  26. Whitmore KE, Payne CK, Diokno AC, Lukban JC. Sacral neuromodulation in patients with interstitial cystitis: a multicenter clinical trial. Int Urogynecol J Pelvic Floor Dysfunct 2003;14(5):305-8;
  27. Bross S, Braun PM, Weiss J, Martinez Portillo FJ, Knoll T, Seif C, Jünemann KP, Alken P. Sacral neuromodulation in patients with nonobstructive, chronic urinary retention: relevance of the carbachol test and influence of associated nerve lession. Aktuelle Urol
    2003;34(3):157-61;
  28. Arlandis Guzmán S, Alapont Alacreu JM, Bonillo García MA, Ruiz Cerdá JL, Martínez Agulló E, Jiménez Cruz F. Peripheral nerve evaluation:indications, technique and results. Actas Urol Esp 2003;27(7):491-500;
  29. Martín Braun P, Arancibia Fernández MI, Martínez Portillo FJ, Seif C, Sotelino Crespo A, Sugimoto S, de Dios Montoto E, Alken P, Jünemann KP. Continuous bilateral sacral neuromodulation as a minimally invasive implantation technique in patients with functional bladder changes. Arch Esp Urol 2003;56(5):497-501;
  30. Bross S, Braun PM, Weiss J, Martinez Portillo FJ, Knoll T, Seif C, Juenemann KP, Alken P. The role of the carbachol test and concomitant diseases in patients with nonobstructive urinary retention undergoing sacral neuromodulation. World J Urol 2003;20(6):
    346-9;
  31. Schurch B, Reilly I, Reitz A, Curt A. Electrophysiological recordings during the peripheral nerve evaluation (PNE) test in complete
    spinal cord injury patients. World J Urol 2003;20(6):319-22;
  32. Seif C, Cherwon E, Martinez Portilló FJ, Alken P, Jünemann KP, Braun PM. Improved sacral neuromodulation in the treatment of the hyperactive detrusor: signal modification in an animal model. BJU Int 2003;91(7):711-5;
  33. Braun PM, Seif C, Bross S, Martinez Portillo FJ, Alken P, Jünemann KP. Stimulation signal modification in a porcine model for suppression of unstable detrusor contractions. Urology 2003;61(4):839-44;
  34. Comiter CV. Sacral neuromodulation for the symptomatic treatment of refractory interstitial cystitis: a prospective study. J Urol
    2003;169(4):1369-73;
  35. Ratto C, Morelli U, Paparo S, Parello A, Doglietto GB. Minimally invasive sacral neuromodulation implant technique: modifications to the conventional procedure. Dis Colon Rectum 2003;46(3):414-7;
  36. Ripetti V, Caputo D, Ausania F, Esposito E, Bruni R, Arullani A. Sacral nerve neuromodulation improves physical, psychological and social quality of life in patients with fecal incontinence. Tech Coloproctol 2002;6(3):147-52;
  37. Scheepens WA, de Bie RA, Weil EH, van Kerrebroeck PE. Unilateral versus bilateral sacral neuromodulation in patients with chronic voiding dysfunction. J Urol 2002;168(5):2046-50;
  38. Scheepens WA, Jongen MM, Nieman FH, de Bie RA, Weil EH, van Kerrebroeck PE. Predictive factors for sacral neuromodulation in chronic lower urinary tractdysfunction. Urology 2002;60(4):598-602;
  39. Ferulano GP, La Manna S, Dilillo S. Sacral neuromodulation in fecal continence disorders. Recenti Prog Med 2002;93(7-8):403-9;
  40. Aboseif S, Tamaddon K, Chalfin S, Freedman S, Kaptein J. Sacral neuromodulation as an effective treatment for refractory pelvic floor dysfunction. Urology 2002;60(1):52-6;
  41. Linares Quevedo AI, Jiménez Cidre MA, Fernández Fernández E, Perales Cabanas L, Briones Mardones G, Pozo Mengual B, Sáenz Medina J, Escudero Barrilero A. Posterior sacral root neuromodulation in the treatment of chronic urinary dysfunction. Actas Urol
    Esp. 2002 Apr;26(4):250-60;
  42. Braun PM, Baezner H, Seif C, Boehler G, Bross S, Eschenfelder CC, Alken P, Hennerici M, Juenemann P. Alterations of cortical electrical activity in patients with sacral neuromodulator. Eur Urol 2002;41(5):562-6;
  43. Kirkham AP, Knight SL, Craggs MD, Casey AT, Shah PJ. Neuromodulation through sacral nerve roots 2 to 4 with a Finetech- Brindley sacral posterior and anterior root stimulator. Spinal Cord 2002;40(6):272-81;
  44. Braun PM, Seif C, Scheepe JR, Martinez Portillo FJ, Bross S, Alken P, Jünemann KP. Chronic sacral bilateral neuromodulation. Using a minimal invasive implantation technique in patients with disorders of bladder function. Urologe A 2002;41(1):44-7:
  45. Malouf AJ, Wiesel PH, Nicholls T, Nicholls RJ, Kamm MA. Short-term effects of sacral nerve stimulation for idiopathic slow transit constipation. World J Surg 2002;26(2):166-70;
  46. Cappellano F, Bertapelle P, Spinelli M, Catanzaro F, Carone R, Zanollo A, De Seta F, Giardiello G; Italian Group of Sacral Neuromodulation (GINS). Quality of life assessment in patients who undergo sacral neuromodulation implantation for urge
    incontinence: an additional tool for evaluating outcome. J Urol 2001;166(6):2277-80;
  47. Ganio E, Ratto C, Masin A, Luc AR, Doglietto GB, Dodi G, Ripetti V, Arullani A, Frascio M, BertiRiboli E, Landolfi V, DelGenio A, Altomare DF, Memeo V, Bertapelle P, Carone R, Spinelli M, Zanollo A, Spreafico L, Giardiello G, de Seta F. Neuromodulation for fecal incontinence: outcome in 16 patients with definitive implant. The initial Italian Sacral Neurostimulation Group (GINS)
    experience. Dis Colon Rectum 2001;44(7):965-70;
  48. Mazo EB, Krivoborodov GG. Temporary sacral neuromodulation in patients with urge incontinence. Urologia 2000;(4):42-6;
  49. Maher CF, Carey MP, Dwyer PL, Schluter PL. Percutaneous sacral nerve root neuromodulation for intractable interstitial cystitis. J
    Urol 2001;165(3):884-6.
  50. Carey M, Fynes M, Murray C, Maher C. Sacral nerve root stimulation for lower urinary tract dysfunction: overcoming the problem of lead migration. BJU Int 2001;87(1):15-8;
  51. Swinn MJ, Kitchen ND, Goodwin RJ, Fowler CJ. Sacral neuromodulation for women with Fowler’s syndrome. Eur Urol 2000;38(4):
    439-43;
  52. Weil EH, Ruiz-Cerdá JL, van den Bogaard AE, van Kerrebroeck PE. Novel test lead designs for sacral nerve stimulation: improved passive fixation in an animal model. J Urol 2000;164(2):551-5;
  53. Wang Y, Hassouna MM. Neuromodulation reduces c-fos gene expression in spinalized rats: a double-blind randomized study. J Urol
    2000;163(6):1966-70;
  54. Weil EH, Ruiz-Cerdá JL, Eerdmans PH, Janknegt RA, Bemelmans BL, van Kerrebroeck PE. Sacral root neuromodulation in the treatment of refractory urinary urge incontinence: a prospective randomized clinical trial. Eur Urol 2000;37(2):161-71;
  55. Fowler CJ, Swinn MJ, Goodwin RJ, Oliver S, Craggs M. Studies of the latency of pelvic floor contraction during peripheral nerve evaluation show that the muscle response is reflexly mediated. J Urol 2000;163(3):881-3;
  56. van der Aa HE, Alleman E, Nene A, Snoek G. Sacral anterior root stimulation for bladder control: clinical results. Arch Physiol Biochem 1999;107(3):248-56;
  57. Shaker H, Hassouna MM. Sacral root neuromodulation in the treatment of various voiding and storage problems. Int Urogynecol J Pelvic Floor Dysfunct 1999;10(5):336-43;
  58. Ishigooka M, Zermann DH, Doggweiler R, Schmidt RA. Sacral nerve stimulation and diurnal urine volume. Eur Urol 1999;36(5):
    421-6;
  59. Shaker HS, Hassouna M. Sacral nerve root neuromodulation: an effective treatment for refractory urge incontinence. J Urol 1998;159
    (5):1516-9;
  60. Shaker HS, Hassouna M. Sacral root neuromodulation in idiopathic nonobstructive chronic urinary retention. J Urol.1998;159(5):
    1476-8.
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